Angiotensin-converting enzyme (ACE) inhibitors

These medications are often used to treat excessive blood pressure, heart issues, and other conditions.


These medications are often used to treat excessive blood pressure, heart issues, and other conditions.

Angiotensin-converting enzyme (ACE) inhibitors are blood pressure drugs that assist relax the veins and arteries. ACE inhibitors hinder the body’s enzyme from making angiotensin II, a chemical that constricts blood vessels. High blood pressure can result from this constriction, which causes the heart to work harder. Angiotensin II also causes the production of blood pressure-raising hormones.

When using ACE inhibitors

ACE inhibitors are used to prevent, treat, or improve symptoms in a variety of diseases, including:

Blood pressure is high (hypertension)

Coronary artery disease (CAD)

Heart attack


Some chronic kidney disorders

A heart attack

A disorder characterized by skin and connective tissue stiffening (scleroderma)



An ACE inhibitor is sometimes used with another blood pressure drug, such as a diuretic or calcium channel blocker. ACE inhibitors should not be used with an angiotensin-converting enzyme inhibitor or a direct renin inhibitor.

ACE inhibitor examples

There are several ACE inhibitors available. The ideal one for you is determined by a variety of factors, including your general health and pre-existing diseases. People with chronic renal disease, for example, may benefit from taking an ACE inhibitor as one of their drugs.

ACE inhibitors include the following:

Benazepril (Lotensin) (Lotensin)

Enalapril Captopril (Vasotec)


Lisinopril (Prinivil, Zestril)


Quinapril Perindopril (Accupril)

Ramipril (Altace)



Adverse consequences

ACE inhibitors may cause the following side effects:

Coughing that is dry

Blood potassium levels have risen (hyperkalemia)


Dizziness caused by a drop in blood pressure


Taste deterioration

ACE inhibitors can occasionally induce swelling in certain tissues (angioedema). If there is swelling in the throat, it might be fatal.


Nonsteroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen (Advil, Motrin IB, and others) and naproxen sodium (Aleve) reduce ACE inhibitor efficacy. Taking these drugs on occasion should not alter how an ACE inhibitor functions, but see your doctor if you often take NSAIDs.


Taking ACE inhibitors during pregnancy raises the baby’s chance of birth abnormalities. If you are pregnant or want to become pregnant, see your doctor about different ways to control high blood pressure.

Hassan Rajput

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